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To estimate the result of the entire treatment strategy , both progression-free survival and overall survival were estimated for the four organizations from the time of study enrollment, in an evaluation that included all enrolled individuals. All comparative analyses were performed with an intention-to-treat approach for both randomized populations: the consolidation-phase populace, which comprised all sufferers who were permitted receive high-dose melphalan or MPR , and the maintenance-phase human population, which comprised all patients who were eligible to receive lenalidomide maintenance therapy or no maintenance therapy . The safety-analysis population included all patients who received at least one dosage of the scholarly study treatments.