The top of skin had collections of reddish cells, melanocytes and melanin pigment between keratin filaments .. A mole with central dark branches Melanomas that arise in pre-existing moles may initially alter the pigment network within the central region and spare the borders. Case presentation Over a three-month period, a 45-year-old girl noted progressive darkening of a longstanding mole, measuring 6 mm in size, on the dorsum of her right foot . Dermoscopy showed an asymmetrical mole with an irregular pigment network with regional variation in intensity. A darkly pigmented branched component with globules and dots was at the heart of the mole . Excision biopsy showed nests of atypical melanocytes within the epidermis and upper dermis, which were obscured by a marked lymphocytic reaction.For a easy way of reducing the swelling and redness that usually accompanies acne, try crushing an aspirin into a bit of lemon juice and then applying the blend to the most affected regions of the face just before bedtime. Although some social people make use of toothpaste, not really gel, as a spot-treatment on pimples blemishes, this method may actually burn the skin doing more damage than good. Yet another home remedy that some swear by can be taking a zinc supplement tablet every day. 6. Minimize Stress. Stress and tension have more of an impact on the standard of our skin than we may realize, and for some, may directly donate to breakouts or intensify pimples.