According to the evaluation by the federal company, the leading factors that ladies are admitted to the hospital are for pregnancy and childbirth. About 5 million of the 23.2 million medical center admissions for women had been related to delivery. Nearly 2 million hospital stays for women involved cardiovascular disease – the number one killer of women. They included treatment of coronary artery disease, congestive heart failure, heart attacks, atrial fibrillation and other types of irregular heart beat, and chest pain without determined cause.The remaining 65 individuals had Ph-positive disease: 43 with chronic-phase CML, 9 with accelerated-phase CML, 8 with blast-stage CML, and 5 with ALL. The features of the individuals with Ph-positive disease are offered in Table 2Table 2Demographic and Clinical Features of the Ph-Positive Individuals at Baseline. Median follow-up for Ph-positive individuals at the time of evaluation was 66 weeks . Safety Profile Seven dose levels were investigated: 2 mg , 4 mg , 8 mg , 15 mg , 30 mg , 45 mg , and 60 mg . No dose-limiting toxic effects were seen in cohorts getting up to 30 mg. At 45 mg, grade 3 rash constituting a dose-limiting toxicity was reported in a patient with chronic-stage CML. At 60 mg, dose-limiting toxic results were reported in 6 patients in two different cohorts.